Brand Name	:	Eprazole 20 mg, 40mg
Generic Name	:	Esomeprazole
Price	:	BDT: 7.00
Therapeutic Class	:	Antiulcerent Products
Section	:	PPI
Dosages	:	Gastro-esophageal reflux disease (in the presence of erosive reflux  esophagitis), 40 mg once daily for 4 weeks, continued for further 4 weeks if not fully healed or symptoms persist, Symptomatic treatment of Gastro-esophageal reflux disease (in the abse
Indication	:	GERD

Product Details

Composition :

Eprazol 20 Capsule: Each capsule contains Esomeprazole 20 mg as Esomeprazole Magnesium Trihydrate USP in enteric coated pellets.

Eprazol 40 Capsule: Each capsule contains Esomeprazole 40 mg as Esomeprazole Magnesium Trihydrate USP in enteric coated pellets.

Description :

Esomeprazole is the s-isomer of Omeprazole. It is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

Side effects :

Headache, flatulence, nausea, abdominal pain, diarrhea, dry mouth, dizziness/vertigo and constipation. Use in special group :

Pregnancy: Pregnancy category of Esomeprazole is C. There are no adequate and well-controlled studies with Esomeprazole in Pregnant women.

Lactation: The excretion of Esomeprazole in breast milk has not been studied. A decision should be Made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Contraindications :

Patients with known hypersensitivity to any component of the formulation.

Precautions :

Symptomatic response to therapy with Esomeprazole does not preclude the presence of gastric malignancy.

Drug Interaction :

Esomeprazole inhibits gastric acid secretion. Therefore, Esomeprazole may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability (e.g. Ketoconazole, Iron salts and Digoxin).

Storage :

Keep away from light and store below 30oC. Keep out of the reach of children.