Brand Name	:	Cardinor 2.5 mg, 5mg
Generic Name	:	Bisoprolol Hemifumariet
Price	:	BDT: 6.00
Therapeutic Class	:	Hypertension Products
Section	:	Cardiac
Dosages	:	Hypertension: The dose of Bisoprolol must be individualized to the needs of the patients. The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of 5 mg is inadequate, the d
Indication	:	• Hypertension, • Angina, • Congestive heart failure

Product Details

Composition :

Cardinor 2.5 Tablet: Each tablet contains Bisoprolol Fumarate USP 2.5 mg.

Cardinor 5 Tablet: Each tablet contains Bisoprolol Fumarate USP 5 mg.

Description :

Bisoprolol blocks the action of the sympathetic nervous system by blocking the beta1-adrenergic receptors and reduces the heart rate and force of contraction of the heart, thus lowers blood pressure.

Side effects :

Fatigue, dizziness, headache, nausea, vomiting, diarrhoea, constipation or abdominal pain, cold or numb extremities e.g. hands and feet, muscle weakness, bradycardia, peripheral vasoconstriction, bronchospasm, dyspnea.

Pregnancy: Bisoprolol should not be used during pregnancy unless clearly necessary.

Lactation: It is not known whether this drug is excreted in human milk. Therefore, breast-feeding is not recommended during administration of Bisoprolol.

Pediatric use: Safety and effectiveness in pediatric patients have not been established.

Contraindications :

Bisoprolol is contraindicated in patients with asthma, uncontrolled heart failure, prinzmetal's angina, marked bradycardia, hypotension, sick sinus syndrome, second or third degree AV block, cardiogenic shock, metabolic acidosis, severe peripheral arterial disease, sino atrial block etc.

Precautions :

Adjust the dose of Bisoprolol with caution in patients with renal or hepatic impairment.

Drug Interaction :

• Rifampicin accelerates metabolism of Bisoprolol

• Increased risk of bradycardia, AV block and myocardial depression when Bisoprolol is given with amiodarone

• Bisoprolol enhances hypoglycemic effect of insulin

Storage :

Keep away from light and moisture, store in a cool place. Keep out of the reach of children.